Quantifying drug primary mechanism of action parameter in HIV (viral) dynamics

Authors

  • C. P. Ilo Department of Mechanical and Production Engineering, Enugu State University of Science and Technology, Enugu State, Nigeria.
  • S. N. Omenyi Department of Mechanical Engineering, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.
  • I. O. Ani Department of Mechanical and Production Engineering, Enugu State University of Science and Technology, Enugu State, Nigeria.

Keywords:

Human immunodeficiency virus, Drug mechanism of action, Interfacial energetics, Hamaker constant

Abstract

Surface thermodynamics concept was used to quantify drug primary mechanism of action parameter in control infectivity of viral dynamics. The methodology involved expressing interfacial energetics of Hamaker constant, a thermodynamic tool capable of being optimized for disease extinction as drug primary mechanism of action parameter in control infectivity of viral dynamics. The expressed drug primary mechanism of action parameter and the associated drug primary mechanism of action are quantified from imported Hamaker constants data of experimental drugs.

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Published

2021-12-01