Inter-relationship Between Malaria Parasitaemia And Widal Reaction In Febrile Patients

Authors

  • Agbakoba, N.R Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Oseni, S.B Department of Biomedical Sciences, Faculty of Basic Medical Sciences, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4000. Ogbomoso, Oyo State, Nigeria.

Keywords:

Malaria parasitaemia, Widal test, Paratyphi antigens

Abstract

The inter-relationship between malaria parasitaemia and widal reaction in febrile patients was investigated. Malaria and typhoid fever (febrile illnesses) were diagnosed by microscopic malaria parasite presence and Salmonella typhi/paratyphi antibodies screened by Widal reaction with titres greater than or equal to 160 regarded as positive. Of the 797 blood samples investigated. 125 (15.7%) were strictly malaria cases, 429 (53.9%) were mixed infection. 183 (23.0%) were strictly typhoid cases while 60 (7.5%) were negative for both febrile conditions. A co-infection rate of 52.7% and 58.9% was obtained for Salmonella typhi 'O' and 'H' respectively and this was closely followed by S. paratyphi B'O' with a co-infection rate of 41.3%. This positivity rate of S. paratyphi B'O' is significant (P<0.05) and may indicate a possible antigenic similarity with S. typhi and malaria parasite.

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Published

17-12-2007

How to Cite

Agbakoba, N., & Oseni, S. (2007). Inter-relationship Between Malaria Parasitaemia And Widal Reaction In Febrile Patients . Journal of Biomedical Investigation, 5(2), 53–56. Retrieved from https://journals.unizik.edu.ng/jbi/article/view/2615

Issue

Vol. 5 No. 2 (2007)

Section

Articles

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