Endometrial metaplasia in a grand multiparous Nigerian woman; A case report with a review of literature

Obiora Uchendu; Adaeze Phina Uchendu; Akpo Coup Sokoh; Uwhomano OGHOUNU; Osamudia OKHIONKPAMWONYI

doi:10.54117/jcbr.v2i6.6

Authors

Obiora Uchendu Department of Histopathology/Morbid Anatomy, Faculty of Basic Clinical Sciences, Delta State University, Abraka, Nigeria
Adaeze Phina Uchendu Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City, Edo State, Nigeria
Dr. SOKOH Akpo Coup Department of Morbid Anatomy and Histopathology, Delta State University, Abraka, Delta State, Nigeria
Dr. OGHOUNU Uwhomano Best-Link Hospital, Ugheli, Delta State, Nigeria
Dr. OKHIONKPAMWONYI Osamudia Department of Obstetrics and Gynecology, Delta State University Teaching Hospital, Oghara, Delta State, Nigeria.(

DOI:

https://doi.org/10.54117/jcbr.v2i6.6

Keywords:

Endometrium, Metaplasia, Cartilaginous, Over-diagnosis.

Abstract

Metaplasia is the substitution of one class of differentiated somatic cell with another differentiated somatic cell in the same tissue. It is an adaptive response to injurious agents, ranging from microbial to environmental causes.

Two classes of metaplasia have been documented in the endometrium, the more common epithelial metaplasia and the rare mesenchymal metaplasia. Both types have vast morphological forms and may occur in isolation or co-exist with one another. They are frequently overlooked and are major diagnostic pitfalls. Careful clinical and histopathological evaluation are therefore pertinent to avoid over-diagnosis or misdiagnosis. Herein, we report a rare case of cartilaginous metaplasia co-existing with endometrial gland clear cell change in a 45-year old multiparous Nigerian woman, who presented with multiple endometrial polyp.