EPIDEMIOLOGY OF CRYPTOSPORIDIOSIS IN HIV POSITIVE PATIENTS TREATED IN MAJOR TERTIARY/SECONDARY HOSPITALS IN RIVERS STATE, SOUTHERN NIGERIA.

Authors

  • Solomon Nwabueze Ukibe Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Ifeoma M Ekejindu Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Godsplan .U John Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, PMB 5025, Awka, Anambra state, Nigeria.
  • Iloduba N. Aghanya Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Simon Nkpeh Ushie Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Ifeoma S. Anagor Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Ngozi .G Uzoewulu Department of Medical Microbiology and Parasitology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
  • Ugochukwu U. Nwaogwugwu Department of Medicine, Siberian State University, Tomski, Russia.

Keywords:

Cryptosporidiosis, epidemiology, HIV, Rivers, Nigeria

Abstract

Background: Cryptosporidiosis is one of the protozoan, opportunistic infections that are common in HIV positive patients and is characterized by gastroenteritis marked with spurious diarrhea that may lead to death if not treated.

Aim and Objectives: To evaluate the epidemiology of Cryptosporidiosis in HIV positive patients undergoing treatment at University of Port Harcourt Teaching Hospital(UPTH) and Zonal Hospital Ahoada (ZHA), Rivers State, Southern Nigeria.

Materials and Methods: 250 HIV positive patients were randomly recruited for the study consisting of 101 males and 149 females. Demographic data/information was obtained using a well-structured self –administered questionnaire. Stool samples were collected from each of the patients by standard methods. Modified Ziehl Neelsen (MZN) technique was employed to stain thick stool smears which were microscopically examined under high power magnification for the diagnosis of Cryptosporidium species ocysts.

Results: Out of the 250 samples, 19 were positive giving a prevalent rate of 7.6%. The age group with the highest prevalence (2.4%) was 30-40 years followed by 26-30 years (1.6%). The prevalent rate in females (5.6%) was significantly more than that of males (2%) (P < 0.05). Farmers were significantly more affected (3.2%) than other occupational groups (P< 0.05). Patients whose source of domestic water was bore hole had the highest percentage (89.5%) of infection. Personal hygiene (hand washing) had a significant effect on infection rate. Diarrhea was the most frequent presentation of the disease.

Conclusion and Recommendation: Cryptosporidiosis was prevalent in HIV positive patients who presented in UPTH and ZHA in Rivers State, Southern Nigeria. Strict environmental sanitation and provision of portable water are public health measures recommended to reduce the prevalence of this disease especially in HIV/AIDS patients.

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Published

28-07-2023

How to Cite

Ukibe, S. N., Ekejindu, I. M., John, G. .U, Aghanya, I. N., Ushie, S. N., Anagor, I. S., Uzoewulu, N. .G, & Nwaogwugwu, U. U. (2023). EPIDEMIOLOGY OF CRYPTOSPORIDIOSIS IN HIV POSITIVE PATIENTS TREATED IN MAJOR TERTIARY/SECONDARY HOSPITALS IN RIVERS STATE, SOUTHERN NIGERIA. Journal of Biomedical Investigation, 11(2), 116–127. Retrieved from https://journals.unizik.edu.ng/jbi/article/view/2538

Issue

Vol. 11 No. 2 (2023)

Section

Articles

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